* Patients can try NITYR for three weeks for free as long as their doctor prescribes it. Subject to terms and conditions, eligibility criteria, and to other federal and state law.
See offer* For eligible commercially insured patients. Doctor’s prescription required. Subject to terms and conditions and eligibility criteria. Program not available for government-insured patients and subject to other federal and state law.
See offerNITYR (nitisinone) tablets are a new option for treatment of hereditary tyrosinemia (HT-1).
Your patients living with HT-1 may be unaware of this new option for nitisinone (NTBC) – the first in many years – or may have a number of questions regarding the difference compared to the current nitisinone on the market.
NITYR is bioequivalent to Orfadin, which means that it has the same efficacy, safety and side effects, and may offer patients and their families greater convenience – see graph below.
NITYR tablets were designed to be more convenient for your patients because they can be stored at room temperature between 68° and 77°F (20° to 25°C), allowing for excursions between 59° and 86°F (15° and 30°C), with less likelihood of the formation of potentially toxic impurities.
As demonstrated in the graph below, even in accelerated conditions (40°C; 104°F and 75% RH) and over 6 months, NITYR does not surpass the impurity limits established by the FDA.
NITYR does not require refrigeration. They have a shelf life of 36 months (3 years). NITYR tablets are also very small (baby aspirin sized), can be taken with or without food and may have a price advantage compared to the traditional nitisinone on the market (including a $0 co-pay for eligible commercially insured patients).
1 Data on file NIT/02/17 2 Data on file NIT/03/18 3 Data on file NIT/01/17 4 Diet and Low Protein Food Program: Subject to terms and conditions and eligibility criteria. This program is for eligible commercially insured patients only. Not available for government-insured patients and subject to other federal and state law. 5 Free trial offer: Subject to terms and conditions and eligibility criteria. Patients can try NITYR for three weeks for free as long as their doctor prescribes it. Subject to terms and conditions, eligibility criteria, and to other federal and state law. 6 $0 co-pay for eligible commercially insured patients (up to $15,000 per year per patient).
*Orfadin is a registered trademark licensed by Sobi, Inc. or its affiliates.