* Patient can try NITYR for 30 days, one-time, for free, as long as their doctor prescribes it and that have never used NITYR before. Subject to terms and conditions, eligibility criteria, and other federal and state law.
See offer* For eligible commercially insured patients. Doctor’s prescription required. Subject to terms and conditions and eligibility criteria. Program not available for government-insured patients and subject to other federal and state law.
See offerNITYR (nitisinone) Tablets are a new option for treatment of Hereditary Tyrosinemia Type 1 (HT-1).
Your patients living with HT-1 may be unaware of this new option for nitisinone (NTBC) – the first in many years – or may have a number of questions regarding the difference compared to the current nitisinone on the market.
NITYR is bioequivalent to Orfadin capsules, which means that it has the same efficacy, safety and side effects, and may offer patients and their families greater convenience – see graph below.
NITYR Tablets were designed to be more convenient for your patients because they can be stored at room temperature between 68° and 77°F (20° to 25°C), allowing for excursions between 59° and 86°F (15° and 30°C), with less likelihood of the formation of potentially toxic impurities.
As demonstrated in the graph below, even in accelerated conditions (40°C; 104°F and 75% RH) and over 6 months, NITYR does not surpass the impurity limits established by the FDA.
NITYR does not require refrigeration. They have a shelf life of 36 months (3 years). NITYR tablets are also very small (baby aspirin sized), can be taken with or without food and may have a price advantage compared to the traditional nitisinone on the market (including a $0 co-pay 6 for eligible commercially insured patients).
1 Data on file NIT/02/20 2 Data on file NIT/03/18 3 Data on file NIT/01/20 4Wellbeing Program (Low-Protein Food Program and Online Fitness Program): Subject to terms and conditions and eligibility criteria. This program is for eligible commercially insured patients only. Not available for government-insured patients and subject to other federal and state law. Terms, Conditions and eligibility criteria is available at www.nityr.us/offertcs.5 Free NITYR Program: Patients can try NITYR for 30 days, one time, for free, as long as their doctor prescribes it. Subject to terms and conditions, eligibility criteria, and other federal and state law. Terms and Conditions and eligibility criteria are available at www.nityr.us/offertcs.6 $0 co-pay for eligible commercially insured patients (up to $15,000 per year per patient). My Gym is a registered trademark of Gym Consulting LLC. Fit Factory is a registered trademark of Fit Factory LLC. Orfadin is a registered trademark licensed by Sobi, Inc. or its affiliates.