* Patients can try NITYR for three weeks for free as long as their doctor prescribes it. Subject to terms and conditions, eligibility criteria, and to other federal and state law.

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* For eligible commercially insured patients. Doctor’s prescription required. Subject to terms and conditions and eligibility criteria. Program not available for government-insured patients and subject to other federal and state law.

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Safety InformationPrescribing Information

Helping Infants and Young Children with HT-1 Thrive

We understand the many challenges of living with HT-1, but administering nitisinone (NTBC) should not be one of them.

For this reason, NITYR (nitisinone) tablets come in very small1 (baby aspirin sized) and convenient 2 mg, 5 mg, and 10 mg tablets. These tablets can be converted to a tasteless suspension for administration to a younger child via oral syringe, or they can be crushed and added to applesauce (oral syringes and tablet crushers are available for free from the NITYR Patient Support Program). The tablets can be easily disintegrated in an oral syringe and the preparation can be kept in the syringe for up to 24 hours, giving you plenty of time to decide when is the right time to give the medication to your child. NITYR has a 36-month (3 year) shelf life and can be stored at room temperature2.

What I like about NITYR is it’s a really small tablet,” says Carrie. “It comes in the size of baby aspirin, and it can be taken with or without food any time of day. It doesn’t need to be refrigerated.

Carrie - Mother of Ethan, 5 yr old NITYR patient

Administration using an oral syringe

For more information on administering NITYR using an oral syringe, or with applesauce see the full instructions for use or contact the NITYR Patient Support Program on 1-800-847-8714, or refer to the prescribing information.

Administration using Applesauce

  1. Crush one NITYR tablet at a time by placing it between two teaspoons and pushing down lightly on the top spoon. Press, rotate, and look at the tablet. If large particles are still there, repeat until finely crushed. A tablet crusher is also available free of charge. Contact the NITYR Patient Support Team.
  2. Add the tablet powder to one full teaspoon of applesauce in a clean glass or bowl.
  3. If giving more than 1 tablet, repeat the process above, adding the powder to the same applesauce.
  4. Mix well.
  5. Feed the mixture to your child using a teaspoon.
  6. To make sure you give your child all the medicine, add another full teaspoon of applesauce to the same glass or bowl and stir. Again, feed the mixture to your child.
  7. Use the NITYR-applesauce mixture within 2 hours of preparation.

For more information on administering NITYR using an oral syringe, or with applesauce see the full instructions for use, contact the NITYR Patient Support Program on 1-800-847-8714, or refer to the prescribing information.

Designed for Convenience

With your help, your child can lead a full life. With NITYR there is one less thing for you to worry about. If your child is newly diagnosed with HT-1, talk with your healthcare professional about all your treatment options.

NITYR is also stable at room temperature between 68° to 77°F (20° to 25°C), allowing for excursions between 59° and 86°F (15° and 30°C) until its expiry date, freeing you from having to refrigerate the medication. It also has a shelf live of 36 months (3 years). The new formulation can also be taken with or without food, another advantage for families facing vigilant mealtimes every day. A $0 co-pay is also available for eligible commercially insured patients3.

For a family that’s unsure about switching to NITYR, I think I simply would say just give it a try. There is nothing to lose, you have everything to gain,” says Mike. “I think it’s important for caregivers to be open to innovation, because we are such a small community that we don’t always get the attention as some other conditions." "I would tell a new family not to be afraid and to give it a try," adds Carrie. "It was a really positive experience for my son.

Mike and Carrie - parents of Ethan, 5 yr old NITYR patient

1 Data on file NIT/03/18 2 Data on file NIT/01/17 2 $0 co-pay for eligible commercially insured patients (up to $15,000 per year per patient).

Please contact the NITYR Patient Support Program for more information, which is available to you 24/7:

1-800-847-8714
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