NITYR (nitisinone) tablets are the new option to treat babies, adolescents and adults with hereditary tyrosinemia (HT-1). This new option gives parents, as well as adolescents and adults living with HT-1, a choice in their nitisinone (NTBC) treatment.
- Are bioequivalent1 to Orfadin*
- The tablet for all life stages
- Are very small2 (baby asprin sized) and tasteless
- Can be stored at room temperature, do not require refrigeration3 and have a shelf life of 3 years
- Can be taken with or without food
- Have a Food Program4 and a Free Trial5 available
- Have a $0 co-pay for eligible commercially insured patients6
NITYR (nitisinone) tablets - What I Like about NITYR
NITYR is bioequivalent to Orfadin, which means that it has the same efficacy, safety and side effects, and may offer patients and their families greater convenience – see graph.
What I like about NITYR is it’s a really small tablet,” says Carrie. “It comes in the size of baby aspirin, and it can be taken with or without food any time of day. It doesn’t need to be refrigerated.
Carrie - Mother of Ethan, 5 yr old NITYR patient
Cycle Pharmaceuticals truly believes people and families affected by HT-1 deserve more support and guidance. We’ve been working to develop a convenient alternative formulation of nitisinone, one that offers many potential advantages to patients and healthcare professionals alike.
NITYR is very small (baby aspirin sized) and tasteless, and is supplied as 2 mg, 5 mg and 10 mg tablets. Preparing the medication as a suspension is easy and it can be administered using an oral syringe or added to applesauce for babies and younger children.
NITYR can also be taken with or without food and can be stored at room temperature for up to 36 months (3 years) and does not require refrigeration. Because of its high-quality formulation, NITYR is more stable than Orfadin. This means that with NITYR, fewer potentially toxic impurities will form during excursions beyond room temperature.
NITYR Diet and Low Protein Food Program
Cycle Pharmaceuticals has partnered with Cambrooke TherapeuticsTM, a global leader in therapeutic medical nutrition, to support NITYR patients in the purchasing of protein formulas and low protein foods. If you move to NITYR, you will receive a $200 monthly contribution towards therapeutic medical nutrition for 2 years.
For support on how to redeem the monthly $200 contribution, please refer to the NITYR Diet and Low Protein Food Program.
For more details about this Program please contact Cambrooke Therapeutics at 866-456-9776, opt. 2
For a family that’s unsure about switching to NITYR, I think I simply would say just give it a try. There is nothing to lose, you have everything to gain,” says Mike. “I think it’s important for caregivers to be open to innovation, because we are such a small community that we don’t always get the attention as some other conditions.
"I would tell a new family not to be afraid and to give it a try," adds Carrie. "It was a really positive experience for my son.
Carrie and Mike - parents of Ethan, 5 yr old NITYR patient
1 Data on file: NIT/02/17 2 Data on file: NIT/03/18 3 Data on file: NIT/01/17 4 Diet and Low Protein Food Program: Subject to terms and conditions and eligibility criteria. This program is for eligible commercially insured patients only. Not available for government-insured patients and subject to other federal and state law. 5 Free trial offer: Subject to terms and conditions and eligibility criteria. Patients can try NITYR for three weeks for free as long as their doctor prescribes it. Subject to terms and conditions, eligibility criteria, and to other federal and state law. 6$0 co-pay for eligible commercially insured patients (up to $15,000 per year per patient).
*Orfadin is a registered trademark licensed by Sobi, Inc. or its affiliates.