NITYR (nitisinone) Tablets are the new option to treat babies, adolescents and adults with hereditary tyrosinemia type 1 (HT-1). This new option gives parents, as well as adolescents and adults living with HT-1, a choice in their nitisinone (NTBC) treatment.
- Are bioequivalent1 to Orfadin* capsules
- The tablet for all life stages
- Are very small2 (baby asprin sized) and tasteless
- Can be stored at room temperature, do not require refrigeration and have a shelf life of 3 years
- Can be taken with or without food
- Have a COVID-19 Response Wellbeing Program3 and a 30-Day Free NITYR Program4 available
- Have a $0 co-pay for eligible commercially insured patients5
NITYR (nitisinone) Tablets - What I Like about NITYR
NITYR is bioequivalent to Orfadin capsules, which means that it has the same efficacy, safety and side effects, and may offer patients and their families greater convenience – see graph.
What I like about NITYR is it’s a really small tablet,” says Carrie. “It comes in the size of baby aspirin, and it can be taken with or without food any time of day. It doesn’t need to be refrigerated.
Carrie - Mother of Ethan, 5 yr old NITYR patient
Cycle Pharmaceuticals truly believes people and families affected by HT-1 deserve more support and guidance. We’ve been working to develop a convenient alternative formulation of nitisinone, one that offers many potential advantages to patients and healthcare professionals alike.
NITYR is very small (baby aspirin sized) and tasteless, and is supplied as 2 mg, 5 mg and 10 mg tablets. Preparing the medication as a suspension is easy and it can be administered using an oral syringe6 or added to applesauce for babies and younger children.
NITYR can also be taken with or without food and can be stored at room temperature for up to 36 months (3 years) and does not require refrigeration. Because of its high-quality formulation, NITYR is more stable7 than Orfadin. This means that with NITYR, fewer potentially toxic impurities will form during excursions beyond room temperature.
If you are considering NITYR, speak to your HCP, your dietitian or your clinic today – you don’t need to wait until your next appointment. To help you get the most out of the discussion, see our Consultation Guide.
For a family that’s unsure about switching to NITYR, I think I simply would say just give it a try. There is nothing to lose, you have everything to gain,” says Mike. “I think it’s important for caregivers to be open to innovation, because we are such a small community that we don’t always get the attention as some other conditions.
"I would tell a new family not to be afraid and to give it a try," adds Carrie. "It was a really positive experience for my son.
Carrie and Mike - parents of Ethan, 5 yr old NITYR patient
1NIT/02/20 2 Data on file: NIT/03/18 3Wellbeing Program (Low-Protein Food Program and Online Fitness Program): Subject to terms and conditions and eligibility criteria. This program is for eligible commercially insured patients only. Not available for government-insured patients and subject to other federal and state law. Terms, Conditions and eligibility criteria is available at www.nityr.us/offertcs. 4 Free NITYR Program: Patients can try NITYR for 30 days, one time, for free, as long as their doctor prescribes it. Subject to terms and conditions, eligibility criteria, and other federal and state law. Terms and Conditions and eligibility criteria are available at www.nityr.us/offertcs. 5 $0 co-pay for eligible commercially insured patients (up to $15,000 per year per patient). 6Data on file: NIT/01/19. 7Data on file: NIT/01/20 *Orfadin is a registered trademark licensed by Sobi, Inc. or its affiliates. Cambrooke is a registered trademark of Ajinomoto Cambrooke, Inc. My Gym is a registered trademark of Gym Consulting LLC.Fit Factory is a registered trademark of Fit Factory LLC.