* Patient can try NITYR for 30 days, one-time, for free, as long as their doctor prescribes it and that have never used NITYR before. Subject to terms and conditions, eligibility criteria, and other federal and state law.

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* For eligible commercially insured patients. Doctor’s prescription required. Subject to terms and conditions and eligibility criteria. Program not available for government-insured patients and subject to other federal and state law.

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Dietary advice

Healthcare professionals and dieticans will recommend a special, controlled diet - along with medication like NITYR (nitisinone) Tablets – to help children, young adults and adults thrive while living with Hereditary Tyrosinemia Type 1 (HT-1).

A low protein diet individualized for each person with HT-1 is essential. Your healthcare professional and metabolic dietician (an expert in nutritional support for those with HT-1 and other amino acid disorders) can help. They often recommend protein substitutes and supplements based on a patient’s age and dietary needs to help meet their protein requirements. Patients with HT-1 have a highly restricted diet in tyrosine and phenylalanine – amino acids that are present in almost all natural protein sources, such as meat, fish and cheese. Protein requirements instead need to be met from supplements made from alternative proteins like GMP, which is a whole protein derived from whey and does not contain tyrosine or phenylalanine.

NITYR (nitisinone) Tablets - Food Program

Always check with your dietician before starting any new foods for your baby, child or yourself. Certain foods and drinks are generally OK for people with HT-1 – including low protein bread, many fruits and fruit juices, and rice milk. Your dietician can provide a full list. High protein foods like meat, regular bread, cheese, nuts, eggs, soya, beans, lentils and fish are contraindicated, meaning they should never be consumed by someone with HT-1 to prevent serious adverse health effects. Always check food labels to be sure of the ingredients.

Low-protein subsitutes for common foods, known as therapeutic medical nutrition, are available from specialist providers, such as Ajinomoto Cambrooke, Inc., a global leader in therapeutic medical nutrition. These include meat, cheese and chocolate substitutes and can help people with HT-1 to have a varied, and enjoyable, diet.

Many parents find they become experts on avoiding forbidden food and substituting formula and food that helps their child thrive just like any other. As your baby starts socializing with other babies and goes on ‘play dates’ – you’ll learn to pack the best food and snacks ahead of time.

COVID-19 Response Wellbeing Program1

At Cycle Pharmaceuticals, we appreciate that living with HT-1 is not only a matter of treatment, but it involves other daily challenges such as diet management and its related expenses.

Financial help for medical nutrition and online fitness

Given the unprecedented COVID-19 lockdown that shuts down patient access to wellbeing facilities that may seriously impact the health of HT-1 patients, Cycle has developed a COVID-19 Response Wellbeing Program4 for a limited period of time and only for eligible patients with HT-1.

The COVID-19 Response Wellbeing Program includes a Low Protein Food Program and an Online Fitness Program.

The Low-Protein Diet Food Program4 has been created in partnership with with Ajinomoto Cambrooke that eligible HT-1 patients can redeem against medical nutrition for all products available at Cambrooke’s website.

The Online Fitness Program4 has been created in partnership with the leading fitness organizations in partnership with My Gym and Fit Factory, to provide eligible HT-1 patients of all ages with an on-line live program that they can join to support a healthy exercise routine from home, while most groups classes and gyms are closed across the country.


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